A report published in The American Journal of Pathology has revealed the development of simple 3D imaging software for tissue reconstruction and examination which can be directly used by clinicians.
By allowing examination of tissues at a microscopic scale, the system is thought to be able to considerably enhance the study of normal and disease processes, and in particular those that involve structural changes.
Previously, problems with 3D imaging had arisen due to low resolution and difficulties in amassing large quantities of images.
The system can be used on any stained tissue section and generate high-resolution digital images, as well as 3D tissue reconstructions at a cellular resolution level by using automated virtual slide scanners. The scanners automatically digitize the tissue, whilst the software communicates with the imaging software to align the images and produce a visible image in one integrated package.
Leading researcher, Dr. Darren Treanor of the University of Leeds and the Leeds Teaching Hospitals NHS Trust states that the system will be particularly beneficial as it can be used directly by medical staff without the need of input by computing specialists.
“Many fields, including tumor biology, embryology, and cardiovascular disease could benefit from correlation of structure and function in three dimensions, but getting high quality 3D reconstructions has always been difficult. We have demonstrated that our software is accurate and robust enough to use without significant computer science input. This system provides the opportunity for increasing use of 3D histopathology as a routine research tool.”
Original Source Medical News Today
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